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New beating 3D heart tissue may improve cardiac treatment
Scientists have created a 3D heart tissue that beats in synchronised harmony, an advance that may lead to better understanding of cardiac health and improved treatments.
Toronto: Scientists have created a 3D heart tissue that beats in synchronised harmony, an advance that may lead to better understanding of cardiac health and improved treatments.
Researchers at York University in Canada have devised a way to stick three different types of cardiac cells together, like Velcro, to make heart tissue that beats as one.
Until now, most 2D and 3D in vitro tissue did not beat in harmony and required scaffolding for the cells to hold onto and grow, causing limitations.
Researchers made a scaffold free beating tissue outof three cell types found in the heart - contractile cardiac muscle cells, connective tissue cells and vascular cells.
The researchers believe this is the first 3D in vitro cardiac tissue with three cell types that can beat together as one entity rather than at different intervals.
"This breakthrough will allow better and earlier drug testing, and potentially eliminate harmful or toxic medications sooner," said Professor Muhammad Yousaf from York University.
