Food additives cause metabolic syndrome, obesity

Food additives cause metabolic syndrome, obesity
Highlights

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can induce intestinal inflammation, say a new research. The additives alter the gut microbiota composition that promotes the development of inflammatory bowel disease and metabolic syndrome.

New York: Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can induce intestinal inflammation, say a new research. The additives alter the gut microbiota composition that promotes the development of inflammatory bowel disease and metabolic syndrome. Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, afflicts millions of people and is often severe and debilitating.

Metabolic syndrome is a group of very common obesity-related disorders that can lead to type-2 diabetes, cardiovascular and/or liver diseases. Two very commonly used emulsifiers, polysorbate 80 and carboxymethylcellulose that are added to almost all processed foods.

The altered microbiota had enhanced capacity to digest and infiltrate the dense mucus layer that lines the intestine. Alterations in bacterial species resulted in bacteria expressing more flagellin and lipopolysaccharide, which can activate pro-inflammatory gene expression by the immune system.

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