New insight into how brain makes memories

New insight into how brain makes memories
Highlights

Researchers have gained fresh insights into the changes at molecular and cellular level in the brain while forming memories. The findings can help people with Alzheimer\'s get back their memories, the researchers said.

Researchers have gained fresh insights into the changes at molecular and cellular level in the brain while forming memories. The findings can help people with Alzheimer's get back their memories, the researchers said.

Every time we make a memory, somewhere in our brain a tiny filament reaches out from one neuron and forms an electrochemical connection to a neighbouring neuron. The filaments that make these new connections are called dendritic spines and, in a series of experiments, the researchers report that a specific signaling protein, Asef2, plays a critical role in spine formation.
"Alterations in dendritic spines are associated with many neurological and developmental disorders, such as autism, Alzheimer's disease and Down Syndrome," said lead researcher Donna Webb, an associate professor at Vanderbilt University.
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