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The post-Second World War 1940s saw mass production of penicillin — the first antibiotic, discovered in 1928 — and the world’s dependence on this line of medicines grew substantially. More discoveries were made in the decades that followed. But all this stopped by the 1980s. What then happened was not discovery of novel classes of antimicrobials, but reformulation of the same classes of drugs against which bacteria can develop resistance easily
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